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The tripeptide gut hormone infusion GOP, which stands for GLP-1, OXM, and PYY, was investigated in a trial by Behary et al

The upregulated gene clusters are enriched in extracellular matrix components (collagens I and III, decorin, elastin), antioxidant defense systems (superoxide dismutase, glutathione-related enzymes), DNA repair pathways, and anti-inflammatory mediators including IL-10 and TGF-beta family members

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Shah SS, Kantarjian HM, Ravandi F, O'Brien S, Garcia-Manero G, Andreeff M , Konopleva M, Jabbour E, Pierce SR, Borthakur G, Cortes JE